Vanwege het Corona virus is het nog onduidelijk hoe het onderwijs precies verzorgd gaat worden. Zie voor de actuele informatie de betreffende vakpagina’s op Blackboard/Brightspace.

Studiegids

nl en

Drug Delivery

Vak
2020-2021

Admission requirements

Drug Delivery Technology (300 level course 3rd year of bachelor study BFW).

Description

Part 1:
Nanomedicine is defined as the use of nanotechnology in medicine, which covers a broad spectra of in vivo and ex vivo applications ranging from diagnosis to therapeutic interventions. Over the last decades nanomedicine has already started to change the standard procedures how patients are diagnosed or treated.
Besides a general introduction to the concept of nanomedicine, we will focus on the use of nanoparticles in diagnosis and therapy, which made it to clinical realty or advanced stages of clinical development. Thus, we will address liposomes and lipid formulations, therapeutic antibodies and antibody drug conjugates, polymeric drugs, polymeric drug delivery systems and nanoparticle based diagnostics/theranostics. Apart from lectures, students will be involved by preparing and presenting short lectures on a specific topic in nanomedical research. While student presentations are performed in small groups, each topic will be afterwards discussed by the audience.

Part 2:
Vaccines are the most cost effective medical intervention. Vaccines are to a large extent responsible for almost complete elimination of infectious diseases like smallpox, polio, diphtheria and measles. Extensive research in other areas holds promise for therapeutic vaccines against cancer, Alzheimer and atherosclerosis. Vaccinology is a multidisciplinary area ranging from epidemiology and immunology to pharmaceutical sciences and process technology. In this course you will get an overview of the field. We will address, in the form of lectures, vaccine related immunology, delivery and characterization. Case studies on polio vaccines and systems vaccinology will be presented. Apart from lectures, you will be actively involved by working on assignments in small groups on how to develop a vaccine. The results will be presented by you with the aim to discuss the possibilities and problems related to vaccine development.

Course objectives

  • To gain basic insight into fundamental aspects of nanomedicine.

  • To gain basic knowledge on vaccine development from lead finding and concept development to formulation and route of administration.

Timetable

December 2020. The specific schedule will be published on Brightspace.

Mode of instruction

Combination of lectures, student presentations, and discussions.

Assessment method

Two written exams.

Reading list

Will be handed out during the course.

Registration

Application via uSis. Registration closes 14 days before the start of the course.

Contact

Coordinator: Dr. G. Kersten (gideon.kersten@intravacc.nl) and Dr. W. Jiskoot (w.jiskoot@lacdr.leidenuniv.nl)

Remarks

A minimum of 5 participants and a maximum of 25 participants applies to this course. Placement is based on the registration date.

This information is without prejudice. Alterations can be made for next year