Vanwege het Corona virus is het nog onduidelijk hoe het onderwijs precies verzorgd gaat worden. Zie voor de actuele informatie de betreffende vakpagina’s op Blackboard/Brightspace.

Studiegids

nl en

Biomedical Informatics (BMI)

Vak
2020-2021

Admission requirements

Core course in MSc Life Science and Technology, elective course MSc Chemistry
For students with a BSc degree in the Life Sciences such as LST. You should be familiar with fundamental concepts in molecular biology. Experience in programming is not required.

Description

This course is about bioinformatics approaches to omics data analysis in human health and disease.
It will cover
a) bioinformatics data resources (global data sharing for omics data)
b) computational analyses of genomic data (genome sequencing approaches, genome assembly, de novo sequencing, resequencing and variation analysis),
c) computational analyses of transcriptome and proteome data (RNA-Seq and microarray analyses, RNOmics, pathway analysis, functional enrichment/over-representation and protein-protein interaction networks)
d) medical informatics (omics in rare and complex disease studies, principles and problems in managing and sharing patient data)

Course objectives

At the end of the course students

  • will have knowledge of fundamental principles in bioinformatics

  • will understand biomedical applications of bioinformatics analyses

  • will be able to analyse a range of omics data using bioinformatics tools

  • will understand the impact of the omics revolution on biomedical informatics research

Timetable

Schedule information can be found on the website of the programmes. Assignment deadlines are communicated via Brightspace.

Mode of instruction

Lectures, practical classes, literature discussion and assignments

Assessment method

Written examination (50%) and assignments (50%)
If the corona restrictions preclude an on-campus written examination, the final examination will be a time-limited online essay. Such changes to the assessment method are announced via Brightspace a minimum of 10 working days before the originally scheduled exam date.
Practical exercises and online discussions contain material that may be included in the examination.

Reading list

  • Bioinformatics and Functional Genomics, Jonathan Pevsner, publisher John Wiley & Sons Inc, 3rd edition. ISBN: 978-1-118-58178-0

  • Bioinformatics and Functional Genomics online supplement

  • Current bioinformatics literature referenced in the lectures and practical sessions

Registration

Register for this course via uSis

Contact

Dr. K. J. Wolstencroft

Remarks

According to OER article 4.8, students are entitled to view their marked examination for a period of 30 days following the publication of the results of a written examination. Students should contact the lecturer to make an appointment for such an inspection session.