Admission requirements
Successful completion of How To Write A Research Proposal is helpful.
The course will be given at first year Master level. An introductory seminar will review both level and course content at the start of the course.
Description
Period: 16 November 2020 - 11 December 2020
This advanced course combines clinical aspects with fundamental issues in neurobiology, pathogenesis and treatment of stress-related brain diseases. The course is a ‘joint venture’ of the departments of Psychiatry, Radiology and Molecular Cell Biology (section Neurophysiology).
Specific topics are:
Clinical phenotyping, symptoms and diagnosis of depression and anxiety.
Pharmacology of depression and anxiety: efficacy and new drug development.
Epidemiology, genetics and etiology of depression, bipolar disorder, anxiety disorders and post-traumatic stress disorder.
Comorbidity of stress-related syndromes with other CNS diseases (e.g. Duchenne, migraine, epilepsy, anorexia nervosa, post-traumatic stress disorder, fibromyalgia, chronic fatigue syndrome).
Pathogenesis, molecular mechanisms and novel drug targets.
Theoretical and practical experience in stress and depression research in the departments of psychiatry, radiology (section Neuroradiology), molecular cell biology (section neurophysiology) and endocrinology (expert meetings).
Assignments to explore dedicated topics in the form of critical evaluations, research proposals and literature reviews.
The student will report the results in a clinical and preclinical research proposal and in two oral presentations.
This course will particularly work on:
Research competences:
Defining a research question, writing a research proposal, integrate different biomedical disciplines.
Professional competences:
Commitment, digesting other people’s opinions.
Course objectives
Reproduce knowledge of the different forms of psychiatric diseases
Reproduce different animal models for depression
Recognize expert knowledge of the clinical picture of depression
Explain the contribution of stress in the pathogenesis of depression
Explain the stress system
Understanding the genetic contribution in the pathogenesis of depression
Insight in the putative neuronal and molecular mechanisms underlying stress-related psychiatric diseases
Formulate a research question and present a possible approach for addressing this in a research proposal
Formulate a research question and present a possible approach for addressing this in a research proposal
Present and defend research proposal
Formulate a research question and present a possible approach for addressing this in a research proposal
Present and defend research proposal
Timetable
All course and group schedules are published on our LUMC scheduling website or on the LUMC scheduling app.
Mode of instruction
Interactive lectures, patient demonstrations, work groups, active participation in two symposiums.
Assessment method
Clinical and preclinical research proposals; two oral presentations.
Reading list
Registration
Registration for FOS courses, H2W, Scientific Conduct, How to start, Course on Animal Science , and CRiP and Adv concepts courses takes place in lottery rounds in the beginning of July. After the lottery rounds: if you want to register for a course you are kindly asked to contact the student administration at masterbw-courses@lumc.nl.