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Studiegids

nl en

A Clinical Pharmacologist Approach to type 2 Diabetes

Vak
2020-2021

Admission requirements

Adequate knowledge of Pharmacology and (patho-)physiology and pertaining pharmacotherapy.

THIS COURSE WILL NOT BE PART OF THE LECTURE SERIES FOR THE YEAR 2020-2021

Description

For diabetes mellitus (DM), one of the most prevalent chronic disease entities, different pathophysiological mechanisms can be identified. Next to the most common form of type II DM (T2DM), type I diabetes (T1DM), gestational diabetes (GDM) and iatrogenic DM, mainly caused by drug-induced disturbances of glucose homeostasis, can be distinguished. Obviously, therapies to combat DM should be tailored to the underlying pathophysiology . Furthermore, hyperglycemia and other phenomena of DM are risk factors to develop (premature) cardiovascular disease.

Course objectives

In this course, students will learn how to identify key factors in the pathophysiology of diabetes, evaluate currently available compounds related to the underlying pathophysiology, and critically evaluate emerging therapies. To this end, students will learn to assess the value and limitations of animal models and human disease models. In addition to theory, the students will meet patients with diabetes and learn about their difficulty coping with the disease and its sequela. It is expected that the students will develop pharmacology-based ‘solutions’ for the problems that the patients will present to them.

Timetable

May-June 2020. The specific schedule will be published on Brightspace.

Mode of instruction

Lectures, literature reviews and self-study assignments.

Assessment method

Presentation, verbal examination and report.
Presentations and assignments; both will be graded on a scale 0-10 and the final mark (average of both components) has to exceed 5.6 to pass

Reading list

Will be announced during the lectures.

Registration

Application via uSis. Registration closes 14 days before the start of the course or earlier if the maximum number of students is reached.

Contact

Coordinator: Prof. dr. J (Koos) Burggraaf (kb@chdr.nl)

Remarks

A minimum of 5 students and a maximum of 9 students will be admitted. Placement is based on the registration date.

The course will be held at the Centre for Human Drug Research (Zernikedreef 8, Leiden).

THIS COURSE WILL NOT BE PART OF THE LECTURE SERIES FOR THE YEAR 2020-2021

This information is without prejudice. Alterations can be made for next year