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Stem cells, regeneration and development

Vak
2022-2023

Admission requirements

Description

Regenerative medicine is a rapidly moving field that aims to restore functionality of tissue that is lost due to disease or trauma. Restoration of tissue function is achieved by stimulation of the regenerative potential of tissue-resident stem cells, stem cell transplantation, tissue and genetic engineering or a combination of these approaches. This course will provide insight into the current state of scientific developments in regenerative medicine. Given the interdisciplinary nature of the field of regenerative medicine, this course will touch upon different fields such as (stem) cell biology and the (developmental) biology of stem cells that underly the development of different organ systems.

We will address the following topics:

  1. Early embryonic development and pluripotent stem cells
  2. Adult stem cells in different organ systems
  3. Technologies for the exploration of stem cell biology and regenerative medicine
  4. Regenerative medicine and the patient perspective
  5. Gene editing technologies
  6. Current and future developments

Format
The course design will be based on a combination of lectures and Team-Based Learning (TBL) workshops. This means that learning is a combination of individual and team effort, and that the learning outcomes will be partly determined by the teams. This concept requires full time attendance during the course. Topics will be presented in blocks of 3-4 days which will each consist of introductory lectures workshops and student presentations.

Course objectives

The student:

  • Knows about the important cellular events in developmental biology.

  • Can apply knowledge of developmental biology to stem cells in applications in regenerative medicine.

  • Knows about germ cells and fertility and can apply this knowledge to regenerative medicine.

  • Knows about stem cell models for different organ systems (e.g. cardiovascular and muscle) and can apply these to regenerative medicine.

  • Can design and present a research proposal to advance the field of regenerative medicine using the knowledge from this course. This will be in the context of a team.

Timetable

All course and group schedules are published on our LUMC scheduling website or on the LUMC scheduling app.

Mode of instruction

Assessment method

Summative assessment:

  • Written exams (individual exam and team exam with possibility for an appeal on the exam questions).

  • Peer assessment

  • Presentation

Reading list

Will be distributed during the course.

Registration

Registration for FOS courses, H2W, Scientific Conduct, Course on Lab Animal Sciences and CRiP takes place in lottery rounds in the beginning of July. After the lottery rounds: if you want to register for a course you are kindly asked to contact the student administration at masterbms-courses@lumc.nl.

Contact

masterbms-courses@lumc.nl

Remarks