Core course in MSc Chemistry – Chemical Biology, elective course MSc Chemistry, MSc Life Science and Technology.
For students with a BSc in MST, LST or equivalent. Knowledge of organic chemistry at the level of OC-II (BSc in Chemistry, Molecular Science and Technology, Life Science and Technology or a related discipline) is required.
The course provides the theoretical background necessary for in-depth understanding of organic reaction mechanisms. The course will focus on the role of stereo-electronic factors and conformational effects on the reactivity of molecules, identifying relevant HOMO-LUMO interactions and the application of (simplified) thermodynamics and kinetics, transition state theory and equilibria to understand and predict product distribution in organic reactions.
After the course the student has shown
Comprehension/application of reaction mechanisms of the most common transformations in organic chemistry;
Comprehension/application of orbital interactions to predict and rationalize reactivity;
Comprehension/application of stereoelectronic effects to predict and rationalize reactivity;
Comprehension/application of conformational equilibrium and their influence on reactivity;
Understanding of pericyclic reactions;
Prediction of regio- and stereoselectivity of common organic reactions based on reactivty principles;
Schedule information can be found on the website of the programmes.
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For more information, watch the video or go the the 'help-page' in MyTimetable. Please note: Joint Degree students Leiden/Delft have to merge their two different timetables into one. This video explains how to do this.
Mode of instruction
The class will be given through online classes, online tutorials and on campus tutorials.
Written mid-term test (open book, max 1 bonus point)
Written exam (open book, 100% of total grade)
Clayden, Greeves & Warren, Organic Chemistry, 2nd edition, 2012. ISBN: 978-0-19-927029-3
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