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Advanced Cell Biology

Vak
2022-2023

Admission requirements

This course is for MSc students in Biology.

Contact

Coordinator: Prof.dr. A. Briegel
Email: a.briegel@biology.leidenuniv.nl

Description

This course is about advanced cell biology. The course will cover 5 different topics which will all be introduced by one of the lecturers. The topics of this course are: Cytoskeleton, Energy, Cell cycle, Transcription and Transport. Subsequently research papers about each topic are handed out for students to review in groups. After preparation, the selected topics will be presented by these groups to all students and teachers. Special emphasis will be on comparing bacteria to eukaryotes.

Learning goals

After completion of the course, students are able to:

  • Describe important concepts in cell biology (highlighted terms in the theoretical textbook (Alberts)) related to the topics Cytoskeleton, Energy, Cell Cycle, Transcription and Membranes, and explain their contribution to the function, survival, and proliferation of cells. 

  • Explain differences and similarities of these topics in bacteria and eukaryotes. 

  • Explain the research questions, methodology, results and conclusions from the research presented in the expert lectures. 

  • Apply this knowledge to analyze research papers on these topics and evaluate the research described in these papers. 

  • Formulate the key hypothesis, summarize the results and the conclusions of the research papers, and discuss the state-of-the-art of the research field and the contribution to the field and possible research applications of the main findings. 

  • Generate a graphical abstract to convey the scientific content of a research paper. 

Timetable

28 November 2022- 3 March 2023. Programme details will be announced via Brightspace.

Mode of instruction

Lectures, self study, student presentations

Assessment method

Exam, presentations, multiple choice tests (online)

The final grade consists of the following partical grades:

  • 5 Multiple choice tests 10% (2% per test, no minimum grade)

  • Presentation 25% (minimum grade 5.6)

  • Exam I (course topics I, II) 25% (minimum grade 5.6)

  • Exam II (course topic III, IV, V) 40% (minimum grade 5.6)

Inspection and feedback on the examination

Date: three weeks following the exam date, individually with the course coordinator

Brightspace

Powerpoint presentations will be put on Brightspace

Reading list

Compulsory book:
Molecular biology of the cell (5th or 6th edition)

  • Transcription (Ch4 p194-201, Ch6 p299-316, Ch7 p369-392)

  • Cytoskeleton (Ch16 p889-950)

  • Transport (Ch13)

  • Cell cycle/cell division (Ch17)

  • Energy (Ch2)

Registration

Via USIS

Exchange and Study Abroad students, please see the Prospective students website for more information on how to apply.