Admission requirements
Knowledge about basic principles in Molecular Biology, Cellular Communication and Immunology is required.
Description
Cancer will be discussed in all its aspects, from basic genetics to treatment options in the clinic. Therefore, this module deals with general molecular biology, DNA replication and repair, transcription regulation, protein synthesis, molecular biology of viruses, cell cycle regulation, apoptosis, alterations in cell behaviour including the metastatic properties, interaction of tumour cells and stroma, angiogenesis, epidemiology and pathology of cancer, the immunological response to tumours, diagnosis and treatment of cancer, and new therapies on basis of the insights in cancer development.
Course objectives
The student:
explains how changes in molecular processes in a cell result in transformation to cancer (cell cycle, apoptosis, oncogenes and suppressor genes) and how the tumour microenvironment impact cancer progression (heterogeneity, angiogenesis, metastasis and immunity)
classifies tumours on basis of morphology, nomenclature and biological behaviour
translates and extrapolates molecular knowledge of cancer to current and future anticancer therapies
designs, performs and interprets representative experiments frequently used in cancer research
shows skills to report results in oral and written presentations.
Timetable
All course and group schedules are published on MyTimeTable.
The exam dates have been determined by the Education Board and are published in MyTimeTable.
It will be announced in MyTimeTable and/or Brightspace when and how the post-exam feedback will be organized.
Mode of instruction
The major part of the program consists of self-study assignments that are discussed in workgroups. Some of the assignments have to be performed with the computer and answers have to be send by email. There is a practicum that has to be designed and performed. Reports should be presented to prove that the experiments are understood. The experiment is about the oncogenic transformation of cells in culture. A number of insight seminars will be given. Those seminars will discuss research that requires the knowledge that has been studied in this module. The clinical aspects will be illustrated with patient demonstrations.
Assessment method
The exam consists of 36 open questions. It is an open book exam. All practicums and obligatory assignments have to be executed sufficiently.
Reading list
You can find the complete reading list for Biomedical Sciences here.
Registration
To participate in workgroups and exams students must register with uSis.