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Bioanalytical Mass Spectrometry

Vak
2023-2024

Admission requirements

Students of Master Bio-Pharmaceutical Sciences. The course is also open to students from other Master programs. Interested students should then contact the course coordinators to discuss the possibilities.

Description

This course focuses on the techniques, the instrumentation and applications of Mass Spectrometry in bioanalysis. The lectures give all the basics to understand Mass Spectrometry, including principle, ion sources, mass analyzers, detectors, data handling and spectral interpretation. A special attention is also put on separation techniques used in combination with Mass Spectrometry, and how to hyphenate such techniques. Finally, external speakers from university, medical centers, and/or the (pharma) industry highlight how Mass Spectrometry can be used in today’s science, within different bioanalytical applications.

Course objectives

The main objectives of the course BMS is to provide the students with:

  • The basic working principle of mass spectrometry (MS), including background, mechanisms, ionization, instrumentation, spectral interpretation, as well as hyphenation to chromatographic and electrophoretic techniques.

  • The latest developments of MS technology and future trends in bioanalysis.

  • A deep insight of the current MS applications in bioanalysis, biomedical and/or biopharmaceutical research.

Timetable

This course is scheduled for semester 1, period 2.

You will find the timetables for all courses and degree programmes of Leiden University in the tool MyTimetable (login). Any teaching activities that you have sucessfully registered for in MyStudyMap will automatically be displayed in MyTimeTable. Any timetables that you add manually, will be saved and automatically displayed the next time you sign in.

MyTimetable allows you to integrate your timetable with your calendar apps such as Outlook, Google Calendar, Apple Calendar and other calendar apps on your smartphone. Any timetable changes will be automatically synced with your calendar. If you wish, you can also receive an email notification of the change. You can turn notifications on in ‘Settings’ (after login).

For more information, watch the video or go the the 'help-page' in MyTimetable. Please note: Joint Degree students Leiden/Delft have to merge their two different timetables into one. This video explains how to do this.

A detailed course schedule will be published on Brightspace.

Mode of instruction

Lectures, tutorials and self-tuition.

Assessment method

The course will be concluded with an assignment (40%) and an exam (60%) (open questions).

For each individual exam, the grade is expressed either with pass or fail, or by using a decimal integer between 1.0 and 10.0 that should be ≥ 5.5. The final grade is expressed using an integer between 1 and 10 and can be rounded off/up to a half integer, with the exception of the grade 5.5. Final grades between 5.50 and 5.99 will be rounded up to 6.0. The final grade should be 6.0 to successfully complete this course.

The time and manner of the inspection and of the feedback session on the examination are specified in the Brightspace module of the course.

Reading list

Will be announced during the course.

Registration

Every student has to register for courses with the enrollment tool MyStudyMap. There are two registration periods per year: registration for the fall semester opens in July and registration for the spring semester opens in December. Please see this page for more information.

Please note that it is compulsory to both preregister and confirm your participation for every exam and retake. Not being registered for a course means that you are not allowed to participate in the final exam of the course. If you want to retake of the exam of the course without following the lectures, you have to contact the coordinator of the course to see if this is possible (you would have to passed the other assignments of the course in the earlier year).
Confirming your exam participation is possible until ten days before the exam.

Extensive FAQ's on MyStudymap can be found here.

Contact

Coordinator: Ahmed Ali (Ali@lacdr.leidenuniv.nl)
Co-coordinators: Isabelle Boom (i.boom@lacdr.leidenuniv.nl) and Laura Hetzel (l.a.hetzel@lacdr.leidenuniv.nl)

Remarks

A minimum of 5 participants is required. The maximal amount of participants is 40.

This information is without prejudice. Alterations can be made for next year.