For students who want to participate in a clinical oriented Post Doctoral Training (GGZ-Psychologist, Psychotherapist) this course is highly relevant. It offers the opportunity to obtain basic insights in the biological processes which are pivotal in the development and manifestation of psychopathology and a its possible treatment. The last decennium has shown a tremendous increase in studies involving (functional) neuro-imaging, molecular biochemistry, genetics and large scale prospective demographic studies leading to a further insight in aetiology , course and treatment possibilities of psychopathology.
In short, neuroscience is more and more relevant in obtaining insight in cognitive and psychological processes. This development also raises fundamental philosophical and ethical questions: what is cognition, soma, psyche? Conceptually it challenges basic assumptions about normal and abnormal behaviour, emotions and cognitions. What is psychopathology and what is the relation with “body and soul”? Similarly, the role and impact of biological interventions are becoming more relevant and more an issue of debate.
Coördinator
PMJ Haffmans:
Sectie Klinische, Gezondheids- Neuropsychologie
Telefoon: +31 (0)71 527 3377
E-mailadres: p.m.j.haffmans@umail.leidenuniv.nlE. Hoencamp:
Kamer: 2B51
Telefoon: +31 (0)71 527 3377
E-mailadres: ehoencamp@fsw.leidenuniv.nl
Aim(s)
Besides psychopharmacology/pharmacotherapy, biological interventions include light therapy, neuro-magnetic stimulation, electroconvulsive therapy and neuro-vagal stimulation. At the end of the course, we expect the participating student to have some insight and knowledge about the possibilities and limitations of the role of biological factors in the development and treatment of patients with psychopathology.
Literature
Nancy Andreasen , Brave New Brain , Oxford University Press. (chapter 1,2,3,4,5,6,7, 8, 9 en 12)
JoEllen Patterson et al., The Therapist’s Guide to Psychopharmacology, New York, London; The Guilford Press. 2006 (Chapter 1,2,3,4,5,6,7,8, appendix B)
Examination
multiple choice questions and five short essay questions
From January 1, 2006 the Faculty of Social Sciences has instituted the Ephorus system to be used by instructors for the systematic detection of plagiarism in students’ written work. Please see the Additional Rules and Regulations, section 6.
Education method(s)
Seven two hour lectures
Lecture 1: 4 September 2008 (JH)
Basic aspects of psychopharmacology: what are pharmaco-dynamics and pharmaco-kinetics? Basic principles of neurotransmission and neuromodulation. What are effects and side effects? What is the role of non pharmacological factors in the effectiveness of medication, placebo effect?
Literature: Patterson chapter 1,2Lecture 2: 11 September 2008 (EH)
Basic aspects of the relationship between psychopathology and biology. Developmental psychopathology, the impact of time: what is premorbid, prodromal, manifest psychopathology and what are epiphenomena?
Literature: Andreasen chapter 1,2,3,7Lecture 3: 18 September 2008 (EH)
Brain structures, brain functions, brain plasticity and the development of psychopathology. What is neuro-imaging?
Literature: Andreasen chapter 4,5,6Lecture 4: 25 September 2008 (JH)
Biological interventions with an emphasis on psychopharmacology. What types of psychopharmacologic agents are available? Antipsychotics, antidepressants, mood stabilisers, anxiolytics. How to prescribe medication?
Literature: Patterson chapter 3,4,5,6,7Lecture 5: 2 October 2008 (JH)
Psychopharmacology and sleep disorders, ADHD. Why are there differences between man and woman and other current controversies and opportunities in clinical psychopharmacology.
Literature: Andreasen chapter 12; Patterson chapter 8Lecture 6: 9 October 2008 (EH)
Genetics and the concept of “gene environment interaction”. Practical and ethical aspects of genotyping and pre-symptomatic screening for psychopathology.
Literature: Andreasen chapter 5Lecture 7: 16 October 2008 (EH & JH)
Back to psychopathology and biology; the multi facetted way (psycho)-pathology can manifest itself. The example of depressive illness as a whole body disease.
Does medication, psychotherapy and placebo affect brain structure and function?
Questions and Answers.
Application
Enrollment for courses of the first semester will take place from July 7th 2008 10hr, until 25th August 10hr, via U-TWIST. Enrollment for courses of the second semester will take place in January 2009.
NB: Exam registration will take place via U-Twist, and will be open between a month and a week before the (re)exam. Students who don’t register, cannot participate in the exam.
Blackboard
Information on Blackbord available www.blackboard.leidenuniv.nl
Timetable
Roosters post-propedeuse: verdiepingsvakken – voltijd (pdf)
Courses in English (pdf)