Aim:
The student understands how dysregulation of cellular functions caused by genetic changes or by the environment can lead to disease.
The student can explain how the interaction between genes and the environment determines disease manifestations.
Starting with a diagnosis, the student can indicate targets for (pharmaco)therapeutic intervention.
The student can show the differences between monogenetic and polygenic disease.
The student can recognize genetic variation as risk factor for disease.
The student has a global understanding of the genetic diversity that will be encountered in medical practice.
The student has a general overview of the processes involved in genome instability and their relation with diseases such as cancer.
Content:
Using several examples we will demonstrate in this block the impact of modern molecular and cellular research on the understanding and treatment of disease.