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Signal Transduction and Therapy of Cancer



Research projects within the theme ‘Signaling Transduction and Therapy of Cancer’ (STTC) mainly focus on molecular signal transduction and on pathways/networks in drug toxicity & safety, cancer progression and cancer drug resistance. Imaging and computational modeling play an important role in the context of cellular behavior at multiple scales. All research projects are studied at the LACDR division of Toxicology. Computational projects are available for students who have followed the course ‘Computational Biomedical Research’.

Course objectives

The objective of the course is to train students with diverse practical skills in molecular and cellular biology or in computational skills in biomedicine, particularly in the context of cancer and therapeutics. Students will be trained in research design and planning. Students will learn how to perform literature study and academic writing.


Mw. Dr. Y. Zhang

Mode of instruction

The course will consist of two parts: literature study and practical/computational training. Students will be supervised by individual PhD students or postdoctoral researchers.

Assessment method

Literature study: 30%
Practical/Computational part:

  • First research presentation: 10%

  • Final research presentation: 10%

  • Practical/computational skills: 30%

  • Research report: 20%

Admission requirements & Registration

This course is mandatory for and restricted to students who do the Minor ‘Disease Signaling and Drug Targets’ (DSDT). The same admission criteria apply to this course as for the entire Minor DSDT. Alternatively, computational instead of experimental projects are available for students that followed the course ‘Computational Biomedical Research’.