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New Technology Ventures (NTV2):The Entrepreneurial Process

Vak 2016-2017


In the course New Technology Ventures: The Entrepreneurial Process (formerly known as RBB Ventures) you will explore the process of growing new technology ventures (companies) based on opportunities created in science & technology. Core of the course is studying and discussing a number of business cases covering the entrepreneurial process from various angles. In addition, in In-Class Interviews, guest entrepreneurs from the BioScience Park will share their experiences with starting and growing new technology companies.

Schedule & Topics; Location

The weekly course sessions are on Monday nights, 18.30-21.30 hrs in the period from April 10, 2017 until June 19, 2017. The exam is on the evening of Monday, June 26, 2017. Most sessions comprise of a case discussion, some instruction and an in-class interview with an entrepreneur.

Cases and topics of the sessions (subject to change):

1: R&R and Perspective on Entrepreneurship
2: Massachusetts General Hospital/MRI Breakthrough and Technology Transfer
3: Rubix-negotiating a license deal
4: Vermeer, Venture Capital Valuation and Risk-Reward Ratio
5: BetaGolf and Business Model Analysis
6: A123 and Gans-Stern framework
7: Nanogene and Assembling the Start-up Team
8 :VC deal , Crowd Funding and Venture Capital
9: Airtame and Assessing a Business Plan
10 (June 26): Exam

Location of the sessions will probably be Hubspot, Lange Gracht 70, otherwise it will be the LUMC.

Mandatory participation and preparation

The sessions are essentially practicals since they require participation in case discussions and interviews. Participation is therefore mandatory.
Preparation for case discussions is likewise mandatory, may take up to 3 to 4 hours per session, and will be tested.

Enterpreneurial events

In addition to following the course, it is highly recommended that you attend or participate in events such as the Science meets Business Cafe, the Science meets Business Plan Competion, Gulliver, events organized by the student entrepreneur foundation LUGUS, and the Philips Innovation Award. Also there will be activities organized by Hubspot that offer good learning experiences.

Enrollment and course fee

This course is for: MSc students, Ph.D. students, post-docs, university staff and others motivated for creating and working in a new technology venture.
The course is obligatory for students doing the New Technology Ventures track in the specialization Science Based Business.

Enrollment: For this course, it is not possible to register via USIS, instead register through our jot-form

Course fee

  • no fee for university students; for the reader a contribution of 20 Euro’s is required to cover copy right payments.
  • Euro 200 for PhD students for the full course and 120 Euro for the light version,
  • Euro 500 for non-students.
    If applicable, an invoice will be mailed at the beginning of the course.


Grading will be based on class preparation and participation (25%), two essays (group assignments) (25%), and a final examination (50%). To get a grade for the course, you need a pass for all three elements.


By former participants Wouter Bruins and Oleg Guziy .

Course issues & concepts

The cases and supporting readings will illustrate issues and concepts like:

  • what is entrepreneurship and administrative versus entrepreneurial behaviour;
  • the process of and issues in transfer of technology from universities to companies;
  • determining a reasonable royalty rate and negotiating a license agreement;
  • academic versus surrogate entrepreneurship and the role of the scientist in academic spin-offs;
  • the framing of ventures in terms of people, opportunity, context and deal;
  • the phases and critical junctures in the formation of university spin-off companies;
  • factors influencing the early growth of academic spin-offs;
  • options for commercializing science & technology, business models and value creation;
  • the founding team and distribution of equity between company founders;
  • value, valuation and risk/reward ratio in new venture financing;
  • how venture capitalists assess business plans and start-up companies;
  • changes in the funding landscape and the promise of crowd funding.

In-Class interviews

In the In-Class Interviews, guest entrepreneurs share their experiences with starting and growing research based companies. Guest entrepreneurs in latter years were amongst others:

  • Eliane Khoury, CEO of Virus Free Air, Delft
  • Gert-Jan van Baarle, Director of Leiden Probe Microscopy
  • Jaap Blaak, founder and CEO FlexGen; co-founder der VenGen and more
  • Pieter Gaillard, Founder and former CSO of To-BBB
  • Joost Holthuis, Founder and former CEO of “OctoPlus”:
  • Gerard Platenburg, founder and former CEO of ProSensa ; CEO of ISA.
  • Bas Reichert, founder and CEO of BaseClear .
  • Victor Schut, Founder and CBO of ProteoNic
  • Gregg Siegal, founder and CEO Zobio
  • Pieter Slijkerman, co-founder and former manager of ZF-Screens and NewCatch
  • Toon Stegmann, founder and CSO of Virosome Biologicals BV, now CSO of Mymetics
  • Onno van de Stolpe, Founder and CEO of Galapagos

Other New Technology Ventures (NTV) Courses

This course is part of a series of three courses with a course load of 5 EC each: NTV Entrepreneurial Opportunities, NTV Business Planning and NTV The Entrepreneurial Process. These courses arm students and (future) researchers with the basic knowledge of how to spot, assess and exploit an entrepreneurial opportunity based on science & technology, and have been desiged to lower the hurdles for students and researchers for getting involved in the process of starting high-tech ventures. This knowledge will be valuable for those who aspire to one day start their own company or who want to become involved in the process of company creation and development as tech transfer managers, business developers, business advisors, investment managers or serial entrepreneurs.

Organized by Science Based Business.