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Introduction to Computational Thinking (ICT)

Vak 2017-2018

Description

Computational Thinking is an essential skill for the 21st-century. It is a method for problem solving, a prerequisite for learning to write computer scripts and to conduct computational drug research.

In this course, we will explore examples of computational thinking in drug research. We will start with a computational view on mathematical equations, limits, partial derivatives and graphs of functions. We will then explore the structure and use of databases, including data-analysis procedures. Furthermore, we will have a look at algorithms and applications in pharmacology, toxicology, bio- and cheminformatics. A substantial part of the course will be hands-on-training in scripting your own computer programs in R.

Course Objectives

The student is able to:
* Solve mathematical equations, calculate limits and partial derivatives and draw graphs of functions
* Program an R-script to format and analyze a dataset and visualize the data
* Evaluate and apply good practices of data-management
* Set up a basic structure and usage for databases in MySQL
* Select and apply the optimal approach from an array of computational methods, for a given biomedical use case

Reading list

Literature will be provided during the course.

Coordinator

Dhr. Dr. B.D. Lam, Dhr. Dr. S. Wink

Mode of instruction

Practical course, consisting of: lectures, demonstrations, computer exercises, literature research and a group assignment.

Assessment method

Students will be assessed on the following modalities:
* Weekly scripting tests (20%)
* Group data-analysis assignment (20%)
* Exam (60%)
Total grade = 100%

Admission requirements & Registration

This course is mandatory for and restricted to students who do the Minor ‘Computational approach to Disease Signaling and Drug Targets’ (CADSDT; the entire Minor or only Part 1), the Minor ‘Modern Drug Discovery’ (MDD) and the Elective Module ‘DSDT’. The same admission criteria apply to this course as for the respective afore mentioned programs.