The course will describe the quantum mechanical and semi-classical formulation of nuclear magnetic resonance and magnetic resonance imaging, together with their applications and the hardware needed to perform these experiments.
The course will consist of lectures where specific topics will be presented; exercises solved in front of the classroom; and one session when scientific papers will be discussed/presented by groups of students. Specific topics covered are:
• NMR basics: energy levels, quantum mechanics, precession, RF pulses, relaxation, chemical shift, one- and two-dimensional NMR spectroscopy
• MRI basics: k-space, imaging sequences, image contrast, T1- and T2-weighted sequences, instrumentation
• Advanced MRI: fast imaging, angiography, lipid suppression, localized spectroscopy, diffusion and perfusion.
After completing the course, you will be able to:
• understand the basic physics behind the phenomenon of magnetic resonance
• derive and interpret information from NMR spectra and MR images from these first principles
• solve exercises aimed to plan/interpret an MRI/NMR experiment
Mode of instruction
Written examination with closed questions
If required, the exam may be re-taken.
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N.B.Smith and A.G.Webb, Introduction to Medical Imaging: physics, engineering and clinical applications (Cambridge University Press, 2010)
Contactgegevens docent: Dhr Prof.dr. A. Webb
De cursus wordt verzorgd door docenten van het Gorter-centrum (LUMC)