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Depression and other Stress Related Disorders

Vak 2018-2019

Admission requirements

  • Successful completion of How To Write A Research Proposal is helpful.
  • The course will be given at first year Master level. An introductory seminar will review both level and course content at the start of the course.

Description

Period: 19 November 2018 - 14 December 2018

This advanced course combines clinical aspects with fundamental issues in neurobiology, pathogenesis and treatment of stress-related brain diseases.
The course is a ‘joint venture’ of the departments of Psychiatry and Molecular Cell Biology (section Neurophysiology).

Specific topics are:

  • Clinical phenotyping, symptoms and diagnosis of depression and anxiety.
  • Pharmacology of depression and anxiety: efficacy and new drug development.
  • Epidemiology, genetics and etiology of depression and anxiety.
  • Comorbidity of stress-related syndromes with other CNS diseases (e.g. migraine, epilepsy, anorexia nervosa, post traumatic stress disorder, fibromyalgia, chronic fatigue syndrome).
  • Pathogenesis, molecular mechanisms and novel drug targets.
  • Theoretical and practical experience in stress and depression research in the departments of psychiatry, molecular cell biology (section neurophysiology) and endocrinology (expert meetings).
  • Assignments to explore dedicated topics in the form of critical evaluations, research proposals and literature reviews.

The student will report the results in a clinical and preclinical research proposal and in two oral presentations.

This course will particularly work on:
Research competences:
Defining a research question, writing a research proposal, integrate different biomedical disciplines.
Professional competences:
Commitment, digesting other people’s opinions.

Course objectives

  • Reproduce knowledge of the different forms of psychiatric diseases
  • Reproduce different animal models for depression
  • Recognize expert knowledge of the clinical picture of depression
  • Explain the contribution of stress in the pathogenesis of depression
  • Explain the stress system
  • Understanding the genetic contribution in the pathogenesis of depression
  • Insight in the neuronal and molecular mechanisms underlying psychiatric diseases
  • Formulate a research question and present a possible approach for addressing this in a research proposal
  • Formulate a research question and present a possible approach for addressing this in a research proposal
  • Present and defend research proposal
  • Formulate a research question and present a possible approach for addressing this in a research proposal
  • Present and defend research proposal

Timetable

All course and group schedules are published on our LUMC scheduling website or on the LUMC scheduling app.

Mode of instruction

Interactive lectures, patient demonstrations, work groups, active participation in two symposiums.

Course load

Total course load is the amount of EC’s multiplied with 28 hours.

Assessment method

Clinical and preclinical research proposals; two oral presentations.

Blackboard

Blackboard will be used during this course.

Registration

Registration for FOS courses, H2W, Scientific Conduct, How to start, Course on Animal Science , and CRiP and Adv concepts courses takes place in lottery rounds in the beginning of July. After the lottery rounds: if you want to register for a course you are kindly asked to contact the student administration at masterbw-courses@lumc.nl.

Contact

masterbms-courses@lumc.nl