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In-vivo biomolecular interactions underlying diseases (IBID)


Core course in MSc Life Science and Technology, elective course MSc Chemistry

Admission requirements

BSc LST or Cell Biology and Molecular Biology courses of the MSc Chemistry


Studies of in-vivo bio-molecular interactions are essential for our understanding of cellular functioning. Specific in-vivo interactions controlling e.g. cell cycle, differentiation, metabolism, proliferation and apoptosis events will be discussed in normal healthy and in disease-related situations. A strong emphasis will also lie on chemical biology aspects of lysosomal storage diseases. Academic skills of writing, reading scientific articles and giving presentations are included.

At the end of the course students:

  • will have in depth understanding of fundamental cell and molecular biology aspects of normal cell situations

  • will have in depth knowledge of fundamental principles of bio-molecular interactions underlying diseases and understanding of drug target finding relevant for developing novel drugs

  • will have knowledge of the societal impact of cell biology for curing world-wide threatening diseases, such as lysosomal storage diseases and cancer

  • will have developed the ability of writing scientific abstracts

  • can digest a scientific article from the literature

  • will be able to write scientific mini-reviews based on recent cell biology/disease literature.

  • will be able to present orally recent cell-biology/disease related literature

  • will be able to understand the current disease-related cell biology literature that was not discussed

Mode of instruction

Lectures and instructions in scientific writing




Schedule information can be found on the website of the programmes


The course is based on recent Nature Reviews articles relevant for modern cell biology/molecular disease studies and papers of on-going related research in the LIC and in cooperating institutes
Slides presented during the courses


Writing scientific abstracts (20%), oral presentation (20%) and essays (60%)

Contact information

Hans Aerts, Rolf Boot


Register for this course via uSis