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Solid State NMR (SSNMR)


Admission requirements

Elective course MSc Chemistry, MSc LST for students with a BSc in LST, MST, Physics or equivalent.


Theoretical basis of modern Solid State NMR-spectroscopy, non-stationary processes. Introduction into coherent spin dynamics and solid state NMR for materials, and biomolecules.
The basis is the density matrix formalism for non-stationary processes in the solid state, and how to manipulate the dynamics in spin space and real space with a spectrometer, exploring the symmetry of the theoretical description. During the course we will perform computer simulations of NMR experiments for gaining hands-on experience, and there is room for the students bringing in their own favorite pulse sequences for analysis.

Course objectives

At the end of the course students:

  • Will have the analytical skills to mathematically manipulate quantum coherent dynamics with operators, rotations and average Hamiltonian theory

  • Will have the skill to do computer simulations like quantum propagators of 1-D and 2-D NMR pulse sequences; localized spectroscopy depending on the students’ interest

  • Will have the skill of transfer of knowledge: apply principles of coherent dynamics and product to quantum chemistry and quantum biology

  • Will be able to see the density matrix and propagator formalism

  • Will be introduced into the logic of analyzing coherent dynamics in the product of quantum and real space

  • Will be able, after installing the Simpson virtual spectrometer on their own laptop, to simulate their NMR experiments

  • Will gain knowledge about the transfer to quantum chemistry and quantum biology


Schedule information can be found on the website of the programmes. Assignment deadlines are communicated via Brightspace.

Mode of instruction

Lectures. This is an interactive course with a high level of participation from the students with peer-instruction.

Assessment method

The grade assessment for this course consists of three parts:

  • In-class participation in the peer instruction: 40%

  • Simulation of pulse sequences exercises, reports to be handed in: 30%

  • Multiple choice quantitative literacy test: 30%

Reading list

Compulsory reading: M.J. Duer, “Solid State NMR spectroscopy”


Register for this course via uSis


Prof.dr. Huub de Groot


Biennial course; this course will not be given next academic year (2021-22).

According to OER article 4.8, students are entitled to view their marked examination for a period of 30 days following the publication of the results of a written examination. Students should contact the lecturer to make an appointment for such an inspection session.