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Prospectus

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Molecular Cell Biology (MCB)

Course
2020-2021

Admission requirements

Core course for MSc Chemistry – Chemical Biology.
For students with a BSc MST or equivalent. The course will give an overview on the basic principles in molecular cell biology.
This course is not suitable for students with a BSc LST or equivalent. This courses replaces the courses Molecular Biology (MB, 4423MOLBI) and Cell Biology (CEB, 4423CELBI), taught until the academic year 2019-20. Molecular Cell Biology cannot be included in the final examination together with Molecular Biology, Cell Biology or both.

Description

The course introduces the students to the principles of cell biology and Molecular biology. It will start with the fundamental principles of cell-chemistry and biosynthesis for both prokaryotic and eukaryotic species. The role and control/regulation of gene expression, including epigenetics and cell signaling, in relation to cellular diversity in multicellular organisms will discussed in detail. As will be the role of sub-cellular compartments or organellar structures, together with the systems cells use to target proteins to those structures and how post-translational modifications of proteins influence these cellular pathways.
Besides these basics with regard to cell and molecular biology also systems/techniques that can be used to study all these processes will presented. All these aspects of molecular cell biology are being discussed in relation to diseases that results from derailment of these processes, including some potential therapeutic options. The overall goal is that the student will develop an understanding of the importance of knowledge regarding cellular pathways in order to intervein in these in case of a disease.

Course objectives

At the end of the course students:

  • Will have general knowledge of fundamental principles in Molecular Biology and Cell Biology

  • Will have knowledge of the fundamental principles in control of gene expression

  • Will have an overview of the applications of Molecular Biology as a tool to study disease states

  • Will have knowledge of the fundamental principles of molecular derailments causing diseases

  • Can digest and present a summary of a scientific article from the literature

  • Will be able to write abstracts and mini reviews dealing with Molecular Biology and Cell Biology

Timetable

Schedule information can be found on the website of the programmes. Assignment deadlines are communicated via Brightspace.

Mode of instruction

Lectures and instructions in scientific writing

Assessment method

Writing two scientific essays (70%) and two abstracts (30%)

Reading list

Molecular Biology of the Cell, Sixth Edition.
By Bruce Alberts et al.
ISBN-13: 978-0815345244
ISBN-10: 0815345240
Slides presented during the courses

Registration

Register for this course via uSis.

Contact

Dr. Rolf Boot

Remarks

According to OER article 4.8, students are entitled to view their marked examination for a period of 30 days following the publication of the results of a written examination. Students should contact the lecturer to make an appointment for such an inspection session.