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Human Pathology


Admission requirements

Biomedical Sciences courses “Humane Biologie”, “Biomoleculen”, “Cellulaire Communicatie”, “Immunology”, Medical Genetics and “Physiology, Basic and Advanced Concepts” or equivalent courses.


This module is an introduction to general pathology and covers five multidisciplinary themes:

  • general pathology

  • gross anatomy of organ systems;

  • mesenchymal differentiation and pathology of bone;

  • pathology of hereditary cancer

  • nephropathology (nephrosclerosis);

All themes focus on the understanding of pathological processes (etiology, pathogenesis and morphology), and on methodology. The themes are introduced by a macroscopic, microscopic and molecular demonstration of the anatomy of the organ system involved. Biomedical research is indispensable for appropriate diagnosis and therapy, it is important to appreciate the position of the biomedical scientist in health care.

Course objectives

The student:

  • Recognizes, names and describes changes (morphological, structural and molecular alterations) in tissue specimens.

  • Recognizes or deduces the cause of a disease (etiology).

  • Describes pathological processes (pathogenesis) that cause clinical signs and symptoms

  • Recognizes and indicates intervention points for (future) therapy.

  • Indicates actual research subjects regarding the diseases which were subject in the course.

  • Comprehends the functional and anatomical relationships of organ systems

  • Has obtained communication skills that allow them to write and present coherently and convincingly while taking into account modern presentation and writing principles

  • Is able to express and defend one's opinion and connect this to or appreciate opinions of others in discussion


Between semesters, we will transfer from using the scheduling app to using MyTimeTable: all educational activities before 6 February 2023 can be viewed on our LUMC scheduling website or in the scheduling app. View MyTimeTable for your schedule from 6 February onwards.

Mode of instruction

Lectures, work groups, practicals, a journal club, a mini-research symposium, (computer-aided) tutorials and (audio guided) visit to the Anatomical Museum.

Assessment method

Multiple choice and open questions.

Reading list

Required, the latest edition of the following books:

  • V. Kumar et al. Robbins and Cotran Pathological Basis of Disease.

  • K.L. Moore et al. Clinically Oriented Anatomy.

  • B. Alberts et al. Molecular Biology of the Cell.


Registration must be done via MyStudyMap. Registration in MyStudyMap gives you automatic access to the course in Brightspace. For more information, please visit the Leiden University website for students.



The module Human Pathology includes an anatomy practical. This will be only available for regular students and exchanges students from Karolinska. Other exchange students, side-entrance students and premasters are not eligible for this practical. They will get an adjusted exam without questions on gross anatomy of organ systems.