Admission requirements
Advice: Participants should have basic knowledge of Systems Biology, Natural Products or a similar course.
Description
Metabolomics has become an important metabolic profiling tool in life sciences, including studies of metabolic profiling, functional genomics, uncovering biological and physiological phenomenon in chemistry, and interaction between organisms. This course will cover basic natural product chemistry, analytical platforms for metabolomics (NMR, Chromatography, Mass Spectrometry), data interpretation with Multivariate Data Analysis, and example of application of metabolomics to life science. There are three parts of the course: 1) theoretical with the lectures given by international lecturers, 2) practice to learn a workflow of metabolomics and data mining, 3) warp-up: identification of metabolites by spectroscopic data.
Course objectives
At the end of the course students are able to:
1) Describe and explain the concept of metabolomics and compared with that of conventional metabolic studies.
2) Recognize the source of natural products and their characteristics in metabolome.
3) Understand the role of metabolomics in systems biology.
4) Understand the basic of analytical platforms used in metabolomics.
5) Describe the basic of data processing for statistics and multivariate data analysis.
6) Understand the basic of multivariate data analysis in metabolomics.
7) Describe and explain general separation and isolation steps in metabolomics.
8) Describe the integration of analytical data for metabolomics.
9) Recognize primary and secondary metabolites of natural products.
10) Recognize chemical characteristics of primary metabolites.
Timetable
Course structure: 1 week for theory, 1 week for practice, 1 week for wrap-up course for structure elucidation, 1 week for self-study, exam.
In MyTimetable, you can find all course and programme schedules, allowing you to create your personal timetable. Activities for which you have enrolled via MyStudyMap will automatically appear in your timetable.
Additionally, you can easily link MyTimetable to a calendar app on your phone, and schedule changes will be automatically updated in your calendar. You can also choose to receive email notifications about schedule changes. You can enable notifications in Settings after logging in.
Questions? Watch the video, read the instructions, or contact the ISSC helpdesk.
Note: Joint Degree students from Leiden/Delft need to combine information from both the Leiden and Delft MyTimetables to see a complete schedule. This video explains how to do it.
Mode of instruction
Lectures, practice, reading of articles
Assessment method
Written examination (date will be decided during the course)
The final grade is based on:
Written exam, to cover all the lectures: 70%
Attendance: 30%
Minimum grade:
Courses require a minimum, unrounded 5.5 grade to complete.
If a course has 2 or more written partial exams, the minimum grade only applies to the weighted average of the exams.
For partial grades from components other than exams (e.g. practicals, seminars, writing assignments), the bottom grade does apply to the individual components.
Please refer to the Student Charter for an overview of regulations.
Reading list
Basic reading list will be provided 3 months before the course.
Registration
As a student, you are responsible for enrolling on time through MyStudyMap.
In this short video, you can see step-by-step how to enrol for courses in MyStudyMap.
Extensive information about the operation of MyStudyMap can be found here.
There are two enrolment periods per year:
Enrolment for the fall opens in July
Enrolment for the spring opens in December
See this page for more information about deadlines and enrolling for courses and exams.
Note:
It is mandatory to enrol for all activities of a course that you are going to follow.
Your enrolment is only complete when you submit your course planning in the ‘Ready for enrolment’ tab by clicking ‘Send’.
Not being enrolled for an exam/resit means that you are not allowed to participate in the exam/resit.
Contact
Coordinator: Dr. Y. H. Choi
Email: y.h.choi@biology.leidenuniv.nl
Remarks
Maximum capacity: 30 students.
Your registration is not complete if you have not registered for all course components available in MyStudymap (exam, lecture, etc.).
This course is a part of an international workshop (Metabolomics Workshop) organized by Y.H. Choi and R. Verpoorte since 2008. The participants will join together with international participants. For the lectures of metabolomics, 8-10 international guest lecturers will be invited. There is limitation of place for the students of Leiden University (ca. 30 places are available). The course will take place in Sylvius building.
Software
Starting from the 2024/2025 academic year, the Faculty of Science will use the software distribution platform Academic Software. Through this platform, you can access the software needed for specific courses in your studies. For some software, your laptop must meet certain system requirements, which will be specified with the software. It is important to install the software before the start of the course. More information about the laptop requirements can be found on the student website.