Prospectus

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Chromatin Organisation and Function (COF)

Course
2024-2025

Admission requirements

This course is an elective course for MSc Life Science and Technology and MSc Chemistry students
Suitable for students with a BSc in MST or LST. Other candidates should have a solid background in molecular and cell biology.

Description

In this course current topics relating to chromatin organization and genome activity across the three domains of life (eukaryotes, archaea and bacteria) will be discussed. Following an overview of basic concepts of chromatin organization in different species, the interplay of chromatin structure with cellular processes will be discussed. Novel techniques for studying these aspects will be highlighted, as well as novel approaches to manipulate chromatin organization with applications in research and medicine.

Topics will be discussed based on recent review and research articles, as well as current research within the research institute.

Course objectives

At the end of the course students:

  • Will have an overview of the mechanisms by which chromatin is organized across the domains of life, with emphasis on similarities and differences.

  • Will have insight in the effects of chromatin organization on processes occurring in a chromatin context.

  • Will have an overview of novel techniques and approaches to study and manipulate chromatin

  • Will be able to discuss verbally as well as in writing specific topics related to the content of this course

  • Will be able to critically evaluate manuscripts of others and implement feedback in their own manuscripts

  • Can digest and present a summary of a scientific article from the literature

Timetable

Schedule information can be found on the website of the programmes.

In MyTimetable, you can find all course and programme schedules, allowing you to create your personal timetable. Activities for which you have enrolled via MyStudyMap will automatically appear in your timetable.

Additionally, you can easily link MyTimetable to a calendar app on your phone, and schedule changes will be automatically updated in your calendar. You can also choose to receive email notifications about schedule changes. You can enable notifications in Settings after logging in.

Questions? Watch the video, read the instructions, or contact the ISSC helpdesk.

Note: Joint Degree students from Leiden/Delft need to combine information from both the Leiden and Delft MyTimetables to see a complete schedule. This video explains how to do it.

Mode of instruction

Lectures, discussions, lab visits.

Assessment method

  • Essay (50%)

  • Presentation (20%)

  • Review of essays (30%)

Participation in the reviewing of essays and attendance at presentations is obligatory.
Changes to the assessment method will be announced via Brightspace a minimum of 10 working days before the originally scheduled deadline.

Reading list

Articles on the topic of each lecture will be provided via Brightspace. Relevant literature for writing of the essay will need to be identified by the students.

Registration

As a student, you are responsible for enrolling on time through MyStudyMap.

In this short video, you can see step-by-step how to enrol for courses in MyStudyMap.
Extensive information about the operation of MyStudyMap can be found here.

There are two enrolment periods per year:

  • Enrolment for the fall opens in July

  • Enrolment for the spring opens in December

See this page for more information about deadlines and enrolling for courses and exams.

Note:

  • It is mandatory to enrol for all activities of a course that you are going to follow.

  • Your enrolment is only complete when you submit your course planning in the ‘Ready for enrolment’ tab by clicking ‘Send’.

  • Not being enrolled for an exam/resit means that you are not allowed to participate in the exam/resit.

Contact

Remus Dame

Remarks

Assignment deadlines are communicated via Brightspace.

According to OER article 4.8, students are entitled to view their marked examination for a period of 30 days following the publication of the results of a written examination. Students should contact the lecturer to make an appointment for such an inspection session.

Software

Starting from the 2024/2025 academic year, the Faculty of Science will use the software distribution platform Academic Software. Through this platform, you can access the software needed for specific courses in your studies. For some software, your laptop must meet certain system requirements, which will be specified with the software. It is important to install the software before the start of the course. More information about the laptop requirements can be found on the student website.