Admission requirements
This course is mandatory for and restricted to students who do the Minor ‘Computational approach to Disease Signaling and Drug Targets’ (CADSDT; the entire Minor or only Part 1) or the Elective Module DSDT. The same admission criteria apply to this course as for the respective afore mentioned programs.
Description
This course will cover the field of biomarker discovery and the application of biomarkers in drug development and patient care to enable personalized medicine. We discuss the use of high-dimensional molecular profiling technologies such as metabolomics and proteomics in conjunction with computational and state-of-the-art statistical approaches to identify, characterize and interpret biomarkers. The use of these particular techniques and approaches can be considered as systems approaches as they aim to understand biological system-specific changes associated with disease and pharmacological drug action. Examples of applications of biomarkers for diagnostics, disease progression and drug treatment response are presented. At the end of this course the student will have developed a broad overview of different approaches and technologies to discover and apply biomarkers in drug development and patient care.
Course Objectives
- Understanding of the scientific concepts underlying the research field of biomarker research and their application in drug development and personalized medicine.
- Understanding of state-of-the-art biomarker discovery approaches and experimental approaches in the field of biomarker research.
- Understanding of key data analysis and modeling methods used in the field of biomarker research
Timetable
In MyTimetable, you can find all course and programme schedules, allowing you to create your personal timetable. Activities for which you have enrolled via MyStudyMap will automatically appear in your timetable.
Additionally, you can easily link MyTimetable to a calendar app on your phone, and schedule changes will be automatically updated in your calendar. You can also choose to receive email notifications about schedule changes. You can enable notifications in Settings after logging in.
Questions? Watch the video, read the instructions, or contact the ISSC helpdesk.
Note: Joint Degree students from Leiden/Delft need to combine information from both the Leiden and Delft MyTimetables to see a complete schedule. This video explains how to do it.
Always check the detailed schedule on the Brightspace module of each Course 2-3 weeks before the start of the Course for group-specific meetings, (intermediate) deadlines, etc..
Mode of instruction
Lectures
Assignments
Assessment method
The final grade will be the based on the grade of the written exam (individual grade) and assignments according to a 70/30 ratio. Students will pass the course if the grade for the written exam is ≥ 5.0 and their average grade is ≥ 6.
Reading list
Literature will be provided during the course.
Registration
As a student, you are responsible for enrolling on time through MyStudyMap.
In this short video, you can see step-by-step how to enrol for courses in MyStudyMap.
Extensive information about the operation of MyStudyMap can be found here.
There are two enrolment periods per year:
Enrolment for the fall opens in July
Enrolment for the spring opens in December
See this page for more information about deadlines and enrolling for courses and exams.
Note:
It is mandatory to enrol for all activities of a course that you are going to follow.
Your enrolment is only complete when you submit your course planning in the ‘Ready for enrolment’ tab by clicking ‘Send’.
Not being enrolled for an exam/resit means that you are not allowed to participate in the exam/resit.
Contact
Dhr. Dr. J.G.C. van Hasselt
Remarks
Software
Starting from the 2024/2025 academic year, the Faculty of Science will use the software distribution platform Academic Software. Through this platform, you can access the software needed for specific courses in your studies. For some software, your laptop must meet certain system requirements, which will be specified with the software. It is important to install the software before the start of the course. More information about the laptop requirements can be found on the student website.