Prospectus

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iGEM for Master Students

Course
2025-2026

Admission requirements

  • Enrolment is by application only, requiring:
    o CV
    o Motivation letter
    o Interview

  • No automatic right of participation; places are limited > you will be placed on a waiting list pending approval of your application..

  • Integration into the student’s study plan must be approved by the study advisor or examination committee (Please indicate during application procedure).

  • Admission will be based on motivation, knowledge, skills and ability to work in a team. For this purpose, we will conduct interviews with Supervisors and/or the coordinator and prospective candidates.

Open to Master’s students in Biology and related fields, subject to competitive selection. Bachelor students may participate but can only earn up to 18 ECTS (honours course).

Description

The International Genetically Engineered Machine (iGEM) competition is the premier global synthetic biology challenge, where interdisciplinary student teams design, build, and test innovative biological systems using standardized genetic parts. This course offers Master’s students at Leiden University the opportunity to participate in iGEM as a credit-bearing course within the MSc Biology curriculum.
Students will engage in a comprehensive synthetic biology research experience, including project design, experimental execution, scientific communication, teamwork, and public outreach. The course culminates in presenting the project at the international iGEM Giant Jamboree in Paris.

The students independent work is at the center of the iGEM project. It is chosen, planned and executed by the team guaranteeing their ownership of the project. Supervision will be focused to advice and general guidance, while the team is in charge of the project.
This course is designed as an in-depth academic project and is formally part of the theoretical component of the MSc Biology programme. The study load is 24 EC.

Course Objectives

By the end of the course, students will be able to:

  • Independently conduct literature research and formulate research proposals.

  • Independently design and execute experiments in synthetic biology and neighboring fields.

  • Develop and test new methods and techniques relevant to their project.

  • Analyze and interpret experimental data critically.

  • Communicate scientific results effectively through written reports, a wiki website, presentations, and videos.

  • Collaborate professionally within interdisciplinary teams.

  • Engage in public outreach and scientific dissemination.

  • Strictly adhere to the competition rules and safety requirements.

Timetable

  • Duration: Approximately 22 weeks full-time, including experimental work, writing, and presentation phases.

  • Timing: Independent research of literature and open brainstorming (January and February). Writing a research proposal and presentation (March). Planning of the research and public outreach (April/May). Intensive lab work primarily during the summer months, followed by participation in the Giant Jamboree in early autumn and final report submission in the following academic year (November ). Each student will also have a final oral examination of 60 to 90 minutes (November).

Mode of instruction

Independent research of literature and open brainstorming (January and February). Writing a research proposal and presentation (March). Planning of the research and public outreach (April/May). Intensive lab work primarily during the summer months, followed by participation in the Giant Jamboree in early autumn and final report submission in the following academic year (November ). Each student will also have a final oral examination of 60 to 90 minutes (November).

Assessment method

The assessment combines individual and group components to reflect both personal contributions and team outcomes:

Assessment Component: Description - Grading
Individual Written Proposal: Literature review and experimental plan, submitted early in the project - Group, graded
Practical Work: Continuous assessment with oral evaluations at mid-term and end of lab work - Individual, graded
Professional Attitude: Evaluation of communication, responsibility, and teamwork based on rubric and supervisor feedback - Individual, graded
Team Deliverables Project: Proposal presentation, Wiki page and presentation video, reflecting group effort. Participation self-reported - Group, graded
Individual Reflection Report: 1000-1500 word report reflecting on project experience, challenges, and future prospects - Individual, graded
Oral Exam: Oral defense (60-90 minutes) assessing depth of knowledge on project and methods - Individual, graded
Practical work, professional attitude: Assessment of individual practical research skills in the lab, groupmeetings and discussions. Mid-term evaluation with feedback in July/August - Individual, graded

Minimum grade:
Courses require a minimum, unrounded 5.5 grade to complete.

If a course has 2 or more written partial exams, the minimum grade only applies to the weighted average of the exams.
For partial grades from components other than exams (e.g. practicals, seminars, writing assignments), the bottom grade does apply to the individual components.

Please refer to the Student Charter for an overview of regulations.

Reading list

  • Scientific articles and reviews relevant to the project topic (self-study or provided by supervisors).

  • iGEM website and competition resources. (www.igem.org)

  • Standard synthetic biology textbooks and protocols.

Registration

Enrolment is by application only, see Admission Requirements.

As a student, you are responsible for enrolling on time through MyStudyMap.

In this short video, you can see step-by-step how to enrol for courses in MyStudyMap.
Extensive information about the operation of MyStudyMap can be found here.

There are two enrolment periods per year:

  • Enrolment for the fall opens in July

  • Enrolment for the spring opens in December

See this page for more information about deadlines and enrolling for courses and exams.

Note:

  • It is mandatory to enrol for all activities of a course that you are going to follow.

  • Your enrolment is only complete when you submit your course planning in the ‘Ready for enrolment’ tab by clicking ‘Send’.

  • Not being enrolled for an exam/resit means that you are not allowed to participate in the exam/resit.

Contact

For questions regarding the course, application procedures, or supervision, please contact:

Remarks

  • Full-time commitment is required, especially during the summer months and Giant Jamboree (totalling minimum 16 weeks). Individual planning is possible but needs to be approved by the course coordinators.

  • Deadlines for oral exam and final report will be communicated by the coordinator, but will be no later than 30 days after the last day of the Jamboree. Exceptions have to be approved by the board of examiners.

  • Final grading is completed in the academic year following the main research period (typically November/December).

  • The project does not have to be within the student’s specialization, but must align with the MSc Biology program.

  • Teams are supervised by former iGEM students from Leiden