Coordinator
Prof.Dr. J. Memelink; j.memelink@biology.leidenuniv.nl
Description
This caput series focuses on general principles of the regulation of gene expression in eukaryotes at the level of transcription, with emphasis on protein modifications, protein-protein interactions and changes in chromatin structure during gene expression. Specific examples that will be dealt with are the regulation of gene expression involved in cancer and in innate immune responses in animals and plants.
Methods of instruction
Lectures, reading and discussion of an article
Study material
Molecular Biology of the Cell (5th Edition), Alberts et al. Garland Science New York, 2008.
Examination
Written examination with open questions
Course requirements/recommendations
Participants are expected to possess basic knowledge of biochemistry and genetics at BSc level. Some attention will be paid to basics.
Time table
1st semester, once a week, usually on Wednesday morning.
Application (enrolling)
E-mail to coordinator
Prof.Dr. J. Memelink; j.memelink@biology.leidenuniv.nl
Blackboard
Blackboard is used for communication and for course material.
Course objective
This course aims at providing knowledge on the molecular mechanisms of gene expression and on techniques commonly used to study these mechanisms.
Attention is paid to general mechanisms illustrated with specific examples from animals (humans) and plants.
Remarks
Minimum number of participants: 6
For master track MCB and other interested students