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Prospectus

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Molecular Computational Biology

Course
2011-2012

Description

Algorithms: pairwise alignment; phylogeny; physical mapping; gene finding; genome rearrangements; DNA chips and gene networks; sequence alignment heuristics; multiple sequence alignment; bioinformatics tools; linkage analysis. Protein structure prediction: homology modelling; fold recognition; knowledge-based potentials; ab initio structure prediction. RNA structure prediction: energy minimization; folding simulations; comparative analysis; non-canonical base pairs; 3D-modeling; RNomics; search for RNA and RNA motifs in genomic databases.

Website

http://www.liacs.nl/~hoogeboo/mcb/