Admission requirements
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Description
A good study design is very important as poorly designed studies may yield misleading results. In this course study designs both for experimental studies (where an investigator is actively intervening) and for observational studies are considered. Applications are in agricultural, social and bio-medical sciences. A selection of the topics included is:
Experimental designs
Optimal designs
Sample size calculation
Randomized clinical trials
Follow-up studies
Case-control studies
Bias and confounding
Survey sampling
Course objectives
Obtain knowledge on the popular study designs statisticians cope with in the life & behavioral sciences.
Mode of Instruction
Class time will consist of lectures and class discussion of assigned readings and homework problems.
Time Table
For the course days, course location and class hours check the Time Table 2014-15 under the tab “Masters Programme” at <http://www.math.leidenuniv.nl/statscience>
Assessment method
Written Exam.
Exam and resit information about the date can be found in the Time Table 2014-15 pdf document under the tab “Masters Programme” at <http://www.math.leidenuniv.nl/statscience>. The exams take place in the Snellius building, the room will be announced on the electronic billboard, to be found at the opposite of the entrance, the content can also be viewed online at: <http://info.liacs.nl/math/>
If the exam does not take place in the Snellius building, then an announcement will be sent via blackboard
Reading List
Piantadosi S. (2005). Clinical Trials: A Methodologic Perspective, Second Edition. New York, NY: John Wiley & Sons.
Friedman LM, Furberg CD, and DeMets D L. Fundamentals of Clinical Trials. Springer-Verlag, New York. 3rd edition. 1998.
Casella: Statistical design, Springer-Verlag, New York. 2rd edition. 2008.
Internet material provided during the course
Course Registration
Enroll in Blackboard for the course materials and course updates.
To be able to obtain a grade and the ECTS for the course, sign up for the (re-)exam in uSis ten calendar days before the actual (re-)exam will take place. Note, the student is expected to participate actively in all activities of the program and therefore uses and registers for the first exam opportunity.
Exchange and Study Abroad students, please see the Prospective students website for information on how to apply.
Contact information
s [dot] le_cessie [at] lumc [dot] nl
Remarks
- This is a compulsory course in the Master’s programme of the specialisation Statistical Science for the Life & Behavioural sciences.