Admission requirements
General knowledge of the English language, biology, mathematics, physics, and chemistry as required for students to be accepted for Biomedical Sciences.
Description
Period: November 09 – December 18, 2015
The course Physiology, Basic Concepts, consists of five themes.
Theme 1. Cardiovascular System (dr. Steendijk)
Anatomy of the heart
Cardiac electrophysiology
Contraction mechanisms
Excitation-contraction coupling
Vascular anatomy and function
Cardiac function
Cardiovascular interaction
Neurohormonal control
Exercise and heart failure
Patient demonstration
Practical Cardiovascular anatomy
Working group Cardiovascular function
Theme 2. Respiratory System (dr. Teppema)
Anatomy of the lungs
Gas transport in the lungs and in blood
Ventilation-perfusion ratio
Control of breathing
Practical Lung anatomy
Working group Control of breathing
Theme 3. Kidneys (dr. Gaasbeek)
Anatomy of the kidneys
Assessment of renal clearance and blood flow
Regulation of glomular filtration rate and renal blood flow
Tubular transport systems and functions with focus on sodium, chloride, water, urea and glucose
Countercurrent multiplication, urine dilution an concentration
Practical Kidney anatomy
Working group Urine dilution/concentration
Theme 4. Homeostasis
Interactions between vital organ systems
Acid-base regulation
Osmolality and volume regulation
Working group Homeostasis
Course objectives
After having followed this course, the student can:
describe and define the structure and functions of the cardiovascular system, the respiratory system and the kidneys;
relate the functions of these organs/organ-systems to the specific anatomical, mechanical and (with regard to the heart) electrical properties;
describe the role of these organ system in homeostasis of the organism
illustrate by clinical examples how several pathophysiologic conditions of these organs/organ-systems can be viewed from basic physiological principles.
Mode of instruction
Plenary lectures, interactive seminars, patient demonstrations, practicals, working groups, e-learning, rehearsal exams.
Assessment method
Multiple choice exam, taken in three sessions. Partial exam 1: Cardiovascular System (10%); Partial exam 2: Respiratory System (10%), Final exam: All topics (80%).
Reading list
Moore KL: Clinically oriented anatomy (6th edition)
Ross MH: Histology (6th edition)
Boron WF: Medical Physiology (2nd updated edition)
Levick JR: Cardiovascular Physiology (5th edition)
West JB: Respiratory Physiology, The essentials (9th edition)
Koeppen BM , Stanton BA: Renal Physiology (5th edition 2015)
Information for exchange students
This module is part of an English taught semester of the bachelor’s programme in Biomedical Sciences at Leiden University Medical Center. Combining biomedical modules with modules from other programmes in Leiden is difficult or impossible due to different scheduling schemes. Exchange students with sufficient relevant background knowledge in biology/biomedicine are therefore encouraged and advised to choose the entire module package indicated below.
Immunology (BW), 8 EC
Pathogen-Host Interactions part 2, 3 EC
Infection and Immunity in Practice, 3 EC
Physiology, Basic Concepts, 8 EC
Communication in Science for Exchange students, 1 EC