Recommended prior knowledge:
Physiological Basic Concepts and Physiology Advanced Concepts, or equivalent knowledge of physiology obtained through courses elsewhere. Literature: Cardiac electrophysiology: from cell to bedside by Zipes and Jalife (Walaeus library).
Lectures will be given about important subjects related to this course, involving 1) basic cardiac electrophysiology, 2) basics of stem cell biology, 3) basics of gene therapy. At the end of this week the students need to decide what aspects have their particular interest, think about ways to study these aspects, and present their ideas in a plenary session. Throughout the week a number of scientific articles will be discussed.
The students, which are operating in duos, will meet the PhD students, visit the labs and start their experiments. Throughout the week a number of scientific articles will be discussed.
The students will continue with their experiments in the lab. The course will be closed by the students presenting their work. In addition, they will submit their abstracts and/or proposal for future experiments.
This course will particularly work on:
How to design and perform experiments.
Commitment, motivation and drive, assertiveness and making a mark
To get a good understanding into:
the underlying mechanisms of electrical interactions in the heart and how this could contribute to proper cardiac function and cardiac dysfunction.
how cell transplantation or cell modification in the damaged heart could affect such electrical interactions in their own typical way.
how to design and perform experiments to study electrical interactions in different cell culture systems.
Mode of instruction
Plenary seminars, practical work in lab, self study assignments.
Abstract and/or grant proposal; oral presentation; student behaviour (motivation, independency, oral reporting, participation in discussion).