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Human Pathology



Monday March 26th – Thursday April 26th 2018.

Admission requirements

Biomedical Sciences courses “Humane Biologie”, “Biomoleculen”, “Cellulaire Communicatie”, “Immunology”, “Introduction to the Neurosciences” and “Physiology, Basic and Advanced Concepts” or equivalent courses.


This module is an introduction to general pathology and covers five multidisciplinary themes:

  • neuropathology (Alzheimer’s disease).;

  • gross anatomy of organ systems;

  • cellular pathology and inflammation

  • mesenchymal differentiation and pathology of bone

  • nephropathology (nephrosclerosis);

All themes focus on the understanding of pathological processes (etiology, pathogenesis and morphology), and are introduced by a macroscopic and microscopic demonstration of the anatomy of the organ system involved. Following introductory lectures, the subject matter will be studied and elaborated upon in work groups, practicals, a journal club, mini-research symposia, (computer-aided) tutorials and a visit to the Anatomical Museum. In addition, clinical conferences can be attended to elaborate upon a topic of choice (optional study elements). Biomedical research is indispensable for appropriate diagnosis and therapy, it is important to appreciate the position of the biomedical scientist in health care.

Course objectives

The student:

  • Recognizes, names and describes changes (morphological and structural alterations) in tissue specimens.

  • Recognizes or deduces the cause of a disease (etiology).

  • Describes pathological processes (pathogenesis) that cause clinical signs and symtons

  • Recognizes and indicates intervention points for (future) therapy.

  • Describes the application of knowledge from MSC’s to clinical practice.

  • Provides an overview of the different neuroimaging techniques in dementia.

  • Indicates actual research subjects regarding the diseases which were subject in the course.

  • Comprehends the functional and anatomical relationships of organ systems

  • Has obtained communication skills that allow them to write and present coherently and convincingly while taking into account modern presentation and writing principles

  • Is able to express and defend ones opinion and connect this to or appreciate opinions of others in discussion

Mode of instruction

Lectures, work groups, practicals, a journal club, mini-research symposia, (computer-aided) tutorials and (mp3- guided) visit to the Anatomical Museum.

Assessment method

Multiple Choice and open questions.

Exam dates

  • Exam: Thursday April 26th 2018 from 13.00-15.30h

  • Re-exam: Monday July 16th 2018 from 13.00-15.30h

Reading list

Required, the latest edition of the following books:

  • V. Kumar et al. Robbins and Cotran Pathological Basis of Disease.

  • K.L. Moore et al. Clinically Oriented Anatomy.

  • B. Alberts et al. Molecular Biology of the Cell.