Due to the Corona virus it is unclear how the programmes will take place. For the latest news please check the course page in Blackboard/Brightspace.


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Quantitative Pharmacology


This information is without prejudice. Alterations can be made for next year


This lecture series comprises the theoretical basis and application of quantitative pharmacology and pharmacokinetic-pharmacodynamic (PK-PD) modeling with the purpose of characterizing and predicting the onset, intensity, and duration of drug effects in patients.


Dr. J.G.C. van Hasselt (coen.vanhasselt@lacdr.leidenuniv.nl)

Admission requirements

Students of Bio-Pharmaceutical Sciences. Adequate knowledge of Pharmacology and Statistics.

Mode of Instruction

The course will mainly consist of lectures and group discussions. Active participation in the discussions and self-study skills are required for this course.

Reading list

Will be announced during the course.

Course objectives

  • Understand key concepts inpharmacokinetics and pharmacodynamics processes and their description using pharmacokinetic-pharmacodynamic (PK-PD) models.

  • Understand the basic mathematical principles used in PK-PD models.

  • Understand the basic concepts in quantitative systems pharmacology.

Assessment method

Written Exam (75%), and assignments (25%).


The course is taught in March/April 2020. The specific schedule will be published on Blackboard.


Application via uSis. Registration closes 14 days before the start of the course.


A minimum of 5 participants is required, with a maximum of 25 students. Placement is based on the registration date.