Admission requirements
Elective course MSc Chemistry, MSc Life Science and Technology
For students with a BSc in MST with a major in Chemistry or equivalent. Other candidates should have a solid background in coordination chemistry.
Description
Enzymes are very efficient in activation of small molecules such as O2, N2, CO2 and H2O and redox reactions in general are run very efficiently in Nature. These processes are very important for the overall energy infrastructure of cells. In this course focus lies on how these catalytic reactions take place at the inorganic cofactors and how one can use the same design principles efficiently in artificial catalytic systems.
Topics that will be discussed include
- How Nature deals with Energy
- Coordination Chemistry of Natural Systems
- Electronic Structure & Frontier Orbitals
- Electrochemistry of Molecular Systems
- Electron Transfer in Enzymes
- Proton Coupled Electron Transfer in Enzymes and Molecular Systems
- Hydrogenases and Proton Reduction Catalysis
- The Oxygen Evolving Center of Photosystem II
- Molecular Water Oxidation Catalysts
- Oxygenases
- Oxidases
- Reactive Oxygen Species and how Nature deals with them
- Enzymes of the Carbon Cycle
- Enzymes of the Nitrogen Cycle
Course objectives
At the end of the course students:
will have knowledge of principles of coordination chemistry
will have knowledge of principles in bioinorganic chemistry
will have an overview of the applications of transition metal catalyzed redox reactions in enzymes
will have knowledge of principles in redox catalysis relevant to the conversion of solar energy into chemical fuels and vice versa.
will be able to construct tentative catalytic mechanisms also for reactions that were not discussed
can digest scientific articles related to this course from the literature
are able to predict the electronics and reactivity for a particular transition metal site based on its structure.
Timetable
Schedule information can be found on the website of the programmes
In MyTimetable, you can find all course and programme schedules, allowing you to create your personal timetable. Activities for which you have enrolled via MyStudyMap will automatically appear in your timetable.
Additionally, you can easily link MyTimetable to a calendar app on your phone, and schedule changes will be automatically updated in your calendar. You can also choose to receive email notifications about schedule changes. You can enable notifications in Settings after logging in.
Questions? Watch the video, read the instructions, or contact the ISSC helpdesk.
Note: Joint Degree students from Leiden/Delft need to combine information from both the Leiden and Delft MyTimetables to see a complete schedule. This video explains how to do it.
Mode of instruction
Lectures and exercises
Assessment method
Written exam
Reading list
"Inorganic Chemistry" by Weller, Overton, Rourke and Armstrong, 6th (ISBN 978-0-19964182-6) or 7th edition (ISBN 978-0-19-876812-8)
Scientific papers, lecture slides and exercises will be provided via Brightspace
Registration
As a student, you are responsible for enrolling on time through MyStudyMap.
In this short video, you can see step-by-step how to enrol for courses in MyStudyMap.
Extensive information about the operation of MyStudyMap can be found here.
There are two enrolment periods per year:
Enrolment for the fall opens in July
Enrolment for the spring opens in December
See this page for more information about deadlines and enrolling for courses and exams.
Note:
It is mandatory to enrol for all activities of a course that you are going to follow.
Your enrolment is only complete when you submit your course planning in the ‘Ready for enrolment’ tab by clicking ‘Send’.
Not being enrolled for an exam/resit means that you are not allowed to participate in the exam/resit.
Contact
Remarks
According to OER article 4.8, students are entitled to view their marked examination for a period of 30 days following the publication of the results of a written examination. Students should contact the lecturer to make an appointment for such an inspection session.
Software
Starting from the 2024/2025 academic year, the Faculty of Science will use the software distribution platform Academic Software. Through this platform, you can access the software needed for specific courses in your studies. For some software, your laptop must meet certain system requirements, which will be specified with the software. It is important to install the software before the start of the course. More information about the laptop requirements can be found on the student website.