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Description
Immunology and Vaccine Chemistry
Immunology is one of the key areas in which chemistry is making an increasing difference. Historically, vaccines were made by killing and formulating a disease causing agent. However, tightening regulation for vaccine preparation is forcing the development of new, precisely synthesized, vaccines. New chemistry is essential for this development. After a concise introduction in general immunology and antigen processing, this course will cover recent advances in the field of molecular vaccine design using examples from the current clinical trial literature. Both prophylactic vaccines (to prevent disease) as well as immunotherapies (to clear existing diseases) will be covered.
Literature
Janeway’s Immunobiology, Kenneth Murphy, Garland Science, 2012 and handouts
Assessment method
Written exam
Expected Background
Basic knowledge of organic chemistry, biochemistry and biomolecular chemistry.