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Synthetic Organic Chemistry (SOC)


Admission requirements

BSc MST students with a major in Chemistry, BSc LST students.


Strategies for the synthesis of current of newly developed drugs are discussed, including retro-synthetic analysis, introduction and modification of functional groups and the use of protective groups, control of stereo- and regio-selectivity.

Course Objectives

After the course students:

  • Will have knowledge of the relation of structure and reactivity of organic molecules;

  • Will have knowledge of standard chemical reactions, with a focus on functional group conversions;

  • Will have knowledge of chemical concepts such as delocalization, conjugation, stereochemistry, tautomerism, regio-, chemo- and stereoselectivity, and aromaticity.

  • Will be able to apply the chemical concepts;

  • Will be able to predict the structures of products of standard reactions;

  • Will be able to predict the required reagents for standard reactions;

  • Will be able to describe the mechanism of reactions.

Reading list

  • Organic chemistry, Clayden, Greeves, Warren, Oxford University

  • Literature will be provided during the course.


Dhr. Prof. Dr. G.J. van der Marel

Mode of instruction

Lectures with active participation of the student

Assessment method

Written exam

Admission requirements & Registration

This course is mandatory for students who do the Minor ‘Modern Drug Discovery’ (MDD) and these students will be given priority. Additional places may be available to students outside the minor under the condition that they meet the admission criteria. The same admission criteria apply to this course as for the entire Minor MDD. Application for students outside the Minor MDD occurs via the study advisers of Bio-Pharmaceutical Sciences, LST or MST.