Period
Monday March 5th – Friday March 23rd 2018.
Admission requirements
The course Physiology, Advanced Concepts, is meant for the student who has already followed the course Physiology, Basic Concepts, or has a comparable level of knowledge on cardiovascular, respiratory and renal physiology.
Description
This course focuses on impaired circulation as a result of inflammation, sepsis, endothelial dysfunction, thrombosis, atherosclerosis and vascular remodelling and its consequences for heart, lung and kidney physiology. Subtopics that will be discussed during the course are:
endothelial (dys)function
(ab)normal hemostasis
sepsis
vascular responses to Toll-like receptor activation
inflammatory & ischemic kidney disease
pulmonary arterial hypertension
atherosclerosis, coronary artery disease & myocardial infarction
heart failure: hemodynamic & electrophysiological effects
Course objectives
After having followed this course, students should have a clear understanding of the major pathophysiological processes involved in blood flow impairment and its consequences for heart, lung and kidney function.
Mode of instruction
This course consists of lectures, seminars, working groups and self-study assignments.
Assessment method
Multiple choice exam.
Exam dates
Exam: Friday March 23rd 2018 from 9.00-12.00h
Re-exam: Wednesday July 11th 2018 from 13.00-16.00h
Reading list
Boron, W. & Boulpaep, E., Medical Physiology, 3th ed., 2016, Elsevier.
Levick JR. Introduction to cardiovascular physiology. Fifth edition. 2010. Hodder Arnold, London, United Kingdom.
Robbins and Cotran Pathologic Basis of Disease. V. Kumar, A.K. Abbas, J.C. Aster, 2015, 9th edition, Elsevier, Philadelphia. PA.
Versteeg HH et al. New fundamentals in hemostasis. Physiol Rev. 2013; ;93:327-358.
Other selected scientific papers and parts of other text books.