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Prospectus

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Translational Neuroscience

Course
2019-2020

Admission requirements

Students can enroll for a half minor if they have obtained 60 credits from the first year.

International Students should have an adequate background in Medicine. Admission will be considered based on CV and motivation letter.
For more information, please contact internationalisering@lumc.nl.

Description

During this half-minor, state of the art knowledge on the clinic and pathophysiology of various diseases of brain, mind and muscle is highlighted and we will discuss how to translate clinical problems into adequate neurobiological research models and how to translate findings from basic research into clinical practice. The first five weeks focus on diseases of muscle and peripheral nerve systems, such as myasthenia, Huntington disease and Duchenne. These weeks introduce essential mechanisms and approaches in translational neuroscience. The second five weeks focus on more complex diseases of the central nervous system (like migraine and depression) and factors influencing the homeostasis of the brain, such as neuroendocrine status, stress and circadian rhythms. See also the website of the LUMC profile area Translational Neuroscience : https://www.lumc.nl/research/medical-research-profiles/translational-neuroscience/

Course objectives

  • Recognise and diagnose episodic brain disorders and neurological movement disorders

  • Translate clinical problems in disorders of circadian rhythms, depression/anxiety, vision and hearing, migraine and nerve and muscle diseases into adequate (animal) models

  • Translate fundamental findings in (animal) model research into clinical research and applications in psychiatric and neurological (movement) disorders

  • Based on clinical and pre-clinical translation research in neuroscience evaluate potential new therapeutic possibilities in psychiatric and neurological (movement) disorders

  • Interpret basic mechanisms and techniques in translational neuroscience

  • Critically evaluate and appraise research findings in translational neuroscience

  • In collaboration with other minor students formulate and communicate innovative research proposals tackling fundamental questions in translational neuroscience

Timetable

All course and group schedules are published on our LUMC scheduling website or on the LUMC scheduling app.

Mode of instruction

Lectures, workgroups, patient demonstrations, practicals, laboratory visits, symposia, self-study assignments, student presentations.

Course load

Total course load is the amount of EC’s multiplied with 28 hours.

Assessment

Normative assessments:

  • Written exam: comprised of multiple shorts exams throughout the minor (70%), grades published within 3 weeks after the exam.

  • Paper appraisal (15%) (Written and oral presentations)

  • Research proposal (15%)(Written and oral presentations)

Formative (Pass/Not Pass) assessments: Oral presentations and discussions in individual weeks

Examination committee:
Dr. R. Fronczek, Dr. J. Plomp, Dr. E. Tolner, Prof. dr. N.J.A. van der Wee

Examination dates + debriefing date:
The exam dates can be found on the schedule website.

Attendance: You need to attend all patient demonstrations, work groups, excursions and practicals. If you have been absent without permission twice or more, the coordinator of the specific week will give you an assignment that you will have to pass before you get your grade for that week.

Blackboard

Blackboard will be used during this course.

Reading list

See Blackboard. See https://www.lumc.nl/research/medical-research-profiles/translational-neuroscience/ to get an impression of translational neuroscience in the LUMC.

Registration

Students are required to register for exams through uSis. The registration for a working group is done by handing in your ‘studieplan’.

Contact

Secretariat
Ms. Ingrid Kanbier
Psychiatry, I.Kanbier@lumc.nl

Prof. dr. N.J.A. van der Wee
Psychiatry, n.j.a.van_der_wee@lumc.nl