Period
Monday 21 January 2019 – Friday 1 March 2019.
Admission requirements
General knowledge of the English language, biology, mathematics, physics, and chemistry as required for students to be accepted for Biomedical Sciences.
Description
The course Physiology, Basic Concepts, consists of two main themes.
**Theme 1. Cardiovascular and Respiratory System (prof.dr. Steendijk) **
Anatomy of the heart and vessels
Cardiac electrophysiology and ECG
Molecular mechanisms
Excitation-contraction coupling
Cardiac muscle physiology and cardiac function
Gas exchange and transport
Cardio-pulmonary interaction
Cardio-vascular interaction
Neurohormonal control
Exercise and heart failure
**Theme 2. Kidneys and Homeostasis (dr. Gaasbeek) **
Anatomy of the kidneys
Renal clearance and blood flow
Regulation of glomular filtration rate and renal blood flow
Tubular transport systems and functions
Urine dilution an concentration
Acid-base regulation
Osmolality and volume regulation
Course objectives
The student:
describes and defines the structure and functions of the cardiovascular system, the respiratory system and the kidneys
relates the functions of organs/organ-systems to the specific anatomical, mechanical and (with regard to the heart) electrical properties
describes the role of these organ system in homeostasis of the organism
illustrates by clinical examples how several pathophysiologic conditions of organs/organ-systems can be viewed from basic physiological principles
Mode of instruction
Plenary lectures, interactive seminars, practicals, working groups, e-learning, rehearsal exams.
Assessment method
Two exams. Exam 1: Cardiovascular System (50%); Exam 2: Kidneys and Homeostasis (50%). Final course grade is the average of exam 1 and exam 2, but each individual exam should score at least grade 4.5.
Exam dates
The exam dates can be found on the schedule website.
Reading list
Moore: Clinically oriented anatomy (7th edition, 2013)
Pawlina: Histology (7th edition, 2015)
Boron: Medical Physiology (3rd edition)
Herring, H. & D.J. Paterson: Levick's Introduction to Cardiovascular Physiology. (6th ed. 2018)